Preview·1:00 PM EST·Arrowhead Stadium

Cardinals vs Chiefs Prediction, Picks, Best Bets & Parlay

Free NFL prediction and picks for Sunday, November 22, 2026 · powered by DataStreak

AWAY

Arizona Cardinals

3-6 · L1

HOME

Kansas City Chiefs

6-2 · W1

Cardinals vs Chiefs Prediction

Cardinals at Chiefs, 1:00 PM EST at Arrowhead Stadium.

Two teams, one slate of props, and a model that's been right more than it's been wrong. The plays below earned their spot.

Cardinals vs Chiefs Picks

Books have not posted player props for ARI at KC yet. Lines usually go up a few hours before first pitch or tip-off; check back closer to game time. See all of today’s free picks across the slate.

Injury Report

39 listed

JUST IN: Gardner Minshew II ir → Injured Reserve (Elbow) · Kendrick Bourne out → IR · Michael Wilson ir → Injured Reserve (Neck) · Jalen Brooks out → IR · Zachary Carter ir-r → Injured Reserve (Knee) · Joey Blount questionable → IR · Trey Benson questionable → IR · Will Johnson out → IR · Chase Bisontis out → IR · Kaleb Proctor questionable → IR · Jeremiyah Love out → IR · Tip Reiman pup-p → PUP R · James Conner questionable → IR R · Hjalte Froholdt questionable → Out (Concussion) · Jon Gaines II questionable → Out (Ankle) · Kenny Yeboah ir → Out · Starling Thomas V inactive → Out (Coach's Decision) · Joey Aguilar active → Out (Coach's Decision) · Jayden Williams questionable → Out (Knee) · L'Jarius Sneed questionable → IR · Brashard Smith out → IR · Josh Simmons out → IR · Tyquan Thornton out → IR · Ethan Downs injured-reserve → IR · Omarr Norman-Lott pup-p → PUP R · Kenneth Walker III questionable → Out (Groin) · Jaylon Moore questionable → Out (Ankle) · Garrett Nussmeier inactive → Out (Coach's Decision) · Jaydn Ott questionable → Out (Hamstring) · Ben VanSumeren questionable → Out (Coach's Decision) · Peter Woods questionable → Out (Neck) · Jared Wiley out → Questionable (Ankle)

ARI

Gardner Minshew II
Elbow·Since Nov 8
Injured Reserve
Kendrick Bourne
Since Nov 1
IR
Michael Wilson
Neck·Since Nov 8
Injured Reserve
Jalen Brooks
Since Oct 26
IR
Zachary Carter
Knee·Since Aug 7
Injured Reserve
Joey Blount
Since Aug 8
IR
Trey Benson
Since Aug 15
IR
Will Johnson
Since Sep 20
IR
Chase Bisontis
Since Aug 13
IR
Kaleb Proctor
Since Aug 11
IR
Jeremiyah Love
Since Nov 2
IR
Tip Reiman
Since Aug 6
PUP R
James Conner
Since Aug 15
IR R
Hjalte Froholdt
Concussion·Since Nov 8
Out
Jon Gaines II
Ankle·Since Oct 21
Out
Kenny Yeboah
Since Nov 2
Out
Starling Thomas V
Coach's Decision·Since Feb 28
Out
Joey Aguilar
Coach's Decision·Since Nov 14
Out
Jayden Williams
Knee·Since Nov 14
Out
Eku Leota
Coach's Decision·Since Oct 31
Out
Xavier Weaver
Since Sep 1
Questionable

L'Jarius Sneed
Since Oct 28
IR
Brashard Smith
Since Oct 23
IR
Josh Simmons
Since Sep 2
IR
Tyquan Thornton
Since Oct 4
IR
Ethan Downs
Since Jul 28
IR
Omarr Norman-Lott
Since Feb 28
PUP R
Matt Waletzko
Since Aug 21
IR
Jimmy Holiday
Since Aug 31
IR
John Michael Gyllenborg
Since Jul 28
IR
Kenneth Walker III
Groin·Since Nov 12
Out
Jaylon Moore
Ankle·Since Nov 12
Out
Garrett Nussmeier
Coach's Decision·Since Sep 13
Out
Jaydn Ott
Hamstring·Since Nov 11
Out
Ben VanSumeren
Coach's Decision·Since Oct 24
Out
Peter Woods
Neck·Since Oct 31
Out
Melvin Smith Jr.
Coach's Decision·Since Nov 14
Out
Jared Wiley
Ankle·Since Nov 14
Questionable
Trey Smith
Concussion·Since Nov 14
Questionable

Team Trends

Visit DataStreak for full details

Head-to-Head

KC 4-1 over ARI (1-0 ATS)

Date	Matchup	Score	Winner
2022-09-11	KC @ ARI	44–21	KC
2018-11-11	ARI @ KC	14–26	KC
2014-12-07	KC @ ARI	14–17	ARI
2010-11-21	ARI @ KC	13–31	KC
2006-10-08	KC @ ARI	23–20	KC

Picks, parlays, injuries, trends, and matchup context powered byDataStreak

The Final Word

Numbers in, narrative out. The plays speak for themselves.

Cardinals vs Chiefs FAQ

Where can I find free Cardinals vs Chiefs picks for Sunday, November 22, 2026?

Today's algorithmic plays didn't include Cardinals vs Chiefs, but our full free NFL picks page covers every matchup that did clear the quality bar.

What's the prediction for Cardinals vs Chiefs?

Our prediction is built from team form (records, recent results, win/loss streaks), live moneyline and spread odds across major US books, and DataStreak's algorithmic player-prop research. Every claim on this page is data-backed — no hot takes.

Are these Cardinals vs Chiefs best bets really free?

Yes. Every prediction, pick, and parlay on this page is free, no signup, no paywall.

How is The Cover different from Covers, ATS, or pay-for-pick services?

Three things. (1) Free, full stop — every page, every day. (2) Picks are algorithmic with transparent quality bars (8+ game streak, 75%+ hit rate over 20 games), not opinion columns. (3) Modern UX: live odds, push notifications, comments, mobile-first PWA install.