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49ers vs Cowboys Prediction, Picks, Best Bets & Parlay

Free NFL prediction and picks for Sunday, November 15, 2026 · powered by DataStreak

AWAY
San Francisco 49ers
San Francisco 49ers
6-1 · L1
HOME
Dallas Cowboys
Dallas Cowboys
3-5 · L1

49ers vs Cowboys Prediction

Cowboys are dogs. Big ones. Sometimes the dog hits. The plays below say what to look at.

Prop angles are where the edge lives. Live odds, current streaks, and the picks our partner DataStreak likes are all below.

49ers vs Cowboys Best Bets

Live odds across FanDuel, Caesars, and Bovada. 49ers vs Cowboys moneyline, spread, and current price movement.

via FanDuel
MLSP
49ers-210-4.5 +100
Cowboys+176+4.5 -120

49ers vs Cowboys Picks

Books have not posted player props for SF at DAL yet. Lines usually go up a few hours before first pitch or tip-off; check back closer to game time. See all of today’s free picks across the slate.

Injury Report

34 listed
JUST IN: De'Zhaun Stribling ir → Injured Reserve (Ankle) · Christian Kirk ir → Injured Reserve (Knee - Meniscus) · Nate Hobbs ir-r → Injured Reserve (Groin) · Jake Tonges questionable → IR · Sam Okuayinonu questionable → IR · Isaac Guerendo pup-p → PUP R · Alfred Collins out → IR · Nick Martin active → IR · Darrick Forrest injured-reserve → IR · Ricky Pearsall injured-reserve → IR · Mike Evans questionable → Out (Achilles) · Deebo Samuel questionable → Out (Hamstring) · Brett Toth ir → Questionable · Jonathan Bullard ir-r → Injured Reserve (Calf) · Jalen Thompson ir → Injured Reserve (Hamstring) · Malik Davis out → IR · Princeton Fant questionable → IR · Malachi Lawrence ir → Injured Reserve (Ankle) · Matt Hennessy injured-reserve → IR · KaVontae Turpin questionable → Out (Ribs) · Devin Moore questionable → IR R · George Pickens active → Questionable (Hamstring) · Jake Ferguson out → Questionable (Ankle) · DeMarvion Overshown out → Questionable (Hamstring) · Joey Porter Jr. out → Questionable (Ankle) · Marist Liufau ir-r → Questionable (Forearm) · Luke Schoonmaker out → Questionable (Groin)
SF
  • De'Zhaun Stribling
    Ankle·Since Sep 10
    Injured Reserve
  • Christian Kirk
    Knee - Meniscus·Since Nov 3
    Injured Reserve
  • Nate Hobbs
    Groin·Since Aug 14
    Injured Reserve
  • Jake Tonges
    Since Sep 10
    IR
  • Sam Okuayinonu
    Since Sep 4
    IR
  • Isaac Guerendo
    Since Aug 6
    PUP R
  • Alfred Collins
    Since Sep 7
    IR
  • Nick Martin
    Since Sep 1
    IR
  • Darrick Forrest
    Since May 27
    IR
  • Ricky Pearsall
    Since Aug 6
    IR
  • Nick Zakelj
    Since Aug 31
    IR
  • C.J. West
    Since Sep 23
    IR
  • Mikail Kamara
    Since Aug 3
    IR
  • Mike Evans
    Achilles·Since Oct 19
    Out
  • Deebo Samuel
    Hamstring·Since Nov 5
    Out
  • Austen Pleasants
    Since Aug 31
    IR R
  • Brett Toth
    Since Aug 6
    Questionable
  • Upton Stout
    Shoulder - AC Joint·Since Oct 25
    Questionable
  • Siran Neal
    Knee·Since Nov 3
    Questionable
DAL
  • Jonathan Bullard
    Calf·Since Sep 29
    Injured Reserve
  • Jalen Thompson
    Hamstring·Since Sep 27
    Injured Reserve
  • Malik Davis
    Since Sep 11
    IR
  • Princeton Fant
    Since Aug 6
    IR
  • Malachi Lawrence
    Ankle·Since Nov 1
    Injured Reserve
  • Matt Hennessy
    Since Jun 17
    IR
  • Kelvin Gilliam Jr.
    Since Aug 25
    IR
  • KaVontae Turpin
    Ribs·Since Oct 18
    Out
  • Devin Moore
    Since Aug 31
    IR R
  • George Pickens
    Hamstring·Since Nov 3
    Questionable
  • Jake Ferguson
    Ankle·Since Oct 31
    Questionable
  • DeMarvion Overshown
    Hamstring·Since Nov 4
    Questionable
  • Joey Porter Jr.
    Ankle·Since Nov 4
    Questionable
  • Marist Liufau
    Forearm·Since Aug 31
    Questionable
  • Luke Schoonmaker
    Groin·Since Oct 28
    Questionable

Team Trends

Head-to-Head

SF 4-1 over DAL (3-0 ATS)

DateMatchupScoreWinner
2024-10-28DAL @ SF24–30SF
2023-10-09DAL @ SF10–42SF
2023-01-22DAL @ SF12–19SF
2022-01-16SF @ DAL23–17SF
2020-12-20SF @ DAL33–41DAL
Picks, parlays, injuries, trends, and matchup context powered byDataStreak

The Final Word

Cowboys get blown out or keep it close — doesn't matter to a hit-rate prop. The picks survive the script.

49ers vs Cowboys FAQ

Where can I find free 49ers vs Cowboys picks for Sunday, November 15, 2026?

Today's algorithmic plays didn't include 49ers vs Cowboys, but our full free NFL picks page covers every matchup that did clear the quality bar.

What's the prediction for 49ers vs Cowboys?

Our prediction is built from team form (records, recent results, win/loss streaks), live moneyline and spread odds across major US books, and DataStreak's algorithmic player-prop research. Every claim on this page is data-backed — no hot takes.

Are these 49ers vs Cowboys best bets really free?

Yes. Every prediction, pick, and parlay on this page is free, no signup, no paywall.

How is The Cover different from Covers, ATS, or pay-for-pick services?

Three things. (1) Free, full stop — every page, every day. (2) Picks are algorithmic with transparent quality bars (8+ game streak, 75%+ hit rate over 20 games), not opinion columns. (3) Modern UX: live odds, push notifications, comments, mobile-first PWA install.